In 2020 the whole world, and therefore Solthis, was overwhelmed by the Covid-19 pandemic. Our countries of intervention were affected, particularly with periods of lockdown, requiring major changes to our working practices and prioritisation of our actions. Both our teams per-manently based in the field and those at headquarters in Paris were affected. We immediately had to modify our activities, sometimes suspending them, but we dealt with it together. We can be proud of having maintained our activities in the countries where we work, thanks to the extraordinary mobilisation of our colleagues, alongside our institutional and community partners. Overall, the continuity of the projects has been maintained by adapting to circumstances. In res-ponse to the emergency, we have also initiated additional actions to support healthcare workers and populations affected by Covid-19. This crisis has validated our approach: being close to the populations at the height of the crisis, as we were in the run-up to it, by providing unfailing support to front-line local staff and health systems. Not supplanting but depending on teams who are mainly from the region of West Africa. We must continue along this path, putting the patient at the heart of our action, giving them ownership of their health and freedom of choice. We will continue to fight against communicable and emerging diseases, to respond to the challenges of sexual and reproductive health, of mother and child health, targeting the most vulnerable, particularly women, young girls and children. The crisis has unfortunately made what was already fragile, even more so, making our ambition of universal access to health more difficult to achieve. Yet it has highlighted our unwavering commit-ment to achieving it. Despite the difficulties, you will discover in this report that Solthis has stood firm, and has even made progress towards meeting the essential needs of populations: maintaining and adapting our activities in the field of HIV; but also increasing our support for women and young girls with the launch of the SANSAS, sexual and reproductive health project in Senegal, in addition to our actions in Niger; committing to the ‘One Health’ theme with the Thiellal project in Senegal, signed for 2021, while Covid-19 has shown the importance of responses which incorporate animal and environmen-tal health issues. The year 2021 promises to be at least as complicated as the previous one, difficulty in predicting the outcome of the Covid -19 crisis and its consequences heightens its negative impact on the ability of systems and people to cope now and in the near future. However, you can be sure that our efforts will continue to fulfil our commitment and that Solthis will continue to have the means to improve the health of everyone. These endeavours are driven by the conviction of the importance of our action and by your continued support. Dr Roland Tubiana, President of Solthis Dr Serge Breysse, CEO of Solthis MANDATORY INFORMATION This report was published in June 2021. At the time of printing these pages, the financial report has been certified by KPMG, the auditor, and is subject to ratification at the AGM. Under no circumstances should the inclusion of photos of individuals be interpreted as an indication of their state of health. The Solthis activity report is protected by copyright. The use of all or part of the document is only permissible on condition that the source is credited. Solthis thanks all those who have contributed to this activity report. Editorial and design coordination: Rachel Domenach, Jasmine Irakoze, Juliette Bastin Graphic design and production: www.celinelequeux.com Photo credits: Agence Planet ID Media, ONG AVSF, Bruno Demeocq, Boaz Reise, Erwan Rogard We would also like to offer sincere thanks to Solthis employees and volunteers for their photos. ISSN number: English edition: ISSN 2779-1025, French edition: ISSN 2779-1009